Tetrahydropyrimidine Derivatives: A Potentiometric Study to Determine Dissociation Constant
نویسندگان
چکیده
منابع مشابه
Determination of Dissociation Constants of Some Novel Tetrahydropyrimidine Derivatives in Mixed Organic-Water System by Simple pH Measurement
Some tetrahydropyrimidine derivatives have been synthesized and their structures have been confirmed by IR, 1H NMR, 13C NMR and mass spectral data. The dissociation constants of these derivatives of tetrahydropyrimidine have been measured by Calvin Bjerrum pH titration method in DMF-water (60: 40 v/v) system at 303.15 K. It is observed that dissociation constant depends on substituent groups pr...
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2-Methyl-4-carboxy,5-hydroxy-3,4,5,6-tetrahydropyrimidine (THP(A) or hydroxyectoine) and 2-methyl,4-carboxy-3,4,5,6-tetrahydropyrimidine (THP(B) or ectoine) are now recognized as ubiquitous bacterial osmoprotectants. To evaluate the impact of tetrahydropyrimidine derivatives (THPs) on protein-DNA interaction and on restriction-modification systems, we have examined their effect on the cleavage ...
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Heterocyclic compounds containing a pyrimidine nucleus are of special interests thanks to their applications in medicinal chemistry as they are the basic skeleton of several bioactive compounds such as antifungal, antibacterial, antitumor and antitubercular. As a part of our research in the synthesis of pyrimidine derivatives containing biological activities, some new tetrahydropyrimidine deriv...
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Purpose: In this study, we have focused on antibacterial effect of newly synthesized thiazole, imidazole, and tetrahydropyrimidine derivatives in Iran on listeria monocytogenes. Materials and Methods: For evaluation of antibacterial effect, the disk diffusion method was applied to measure the growth inhibition zone diameter and broth micro dilution was performed to determine the minimum inhibit...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific & Technical Research
سال: 2018
ISSN: 2574-1241
DOI: 10.26717/bjstr.2018.04.000991